{"product_id":"what-have-we-learned-from-treating-melanomas-lvs25","title":"What have we learned from treating melanomas? (LVS25)","description":"\u003cp\u003e20 Nov 2025\u003cbr\u003eRVC Equine Theatre 2\u003c\/p\u003e\n\u003cp\u003eEquine melanocytic tumours, particularly in grey horses, are now recognised as potentially malignant, with up to two-thirds progressing to metastasis. Treatment lessons highlight that early surgical excision, including radical perianal procedures, can provide durable control, while intratumoral cisplatin, electroporation, and emerging immunotherapies offer valuable adjuncts. Future advances lie in targeted, multimodal approaches informed by molecular pathways such as PD-1\/PD-L1 and CD47.\u003c\/p\u003e\n\u003cp\u003eBy the end of this session, delegates will be able to:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eRecognise the epidemiology, genetic basis, and classification of equine melanocytic tumours, and appreciate their potential for malignant progression.\u003c\/li\u003e\n\u003cli\u003eEvaluate the role of surgical excision, including recent evidence supporting radical perianal procedures, in achieving long-term control of extensive melanomas.\u003c\/li\u003e\n\u003cli\u003eDiscuss the effectiveness and limitations of adjunctive treatments such as intratumoral cisplatin, electroporation, radiotherapy, and topical therapies.\u003c\/li\u003e\n\u003cli\u003eUnderstand the promise of immunotherapeutic strategies, including cytokine plasmids and DNA vaccines, for systemic disease management.\u003c\/li\u003e\n\u003cli\u003eAppreciate the need for proactive monitoring and multimodal intervention rather than a “wait-and-see” approach.\u003c\/li\u003e\n\u003cli\u003eIdentify future therapeutic opportunities in targeted and molecular-based treatments (e.g., PD-1\/PD-L1, CD47, COX-2).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eSpeakers\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAlex Hawkins, BSc BVSc MVetMed PGCertVetEd FHEA DipECVS MRCVS, RCVS \u0026amp; EBVS® European Specialist in Equine Surgery, Lecturer in Equine Surgery - Royal Veterinary College\u003c\/p\u003e\n\u003cdiv class=\"m-seminar-entry__item__speakers__speaker\"\u003e\n\u003cdiv class=\"m-seminar-entry__item__speakers__speaker__image\"\u003e\u003cimg height=\"90\" width=\"67\" alt=\"\" src=\"https:\/\/taskfilescsm.s3.amazonaws.com\/uploads\/speaker_thumb\/2022-04-1714%253A24%253A41753882-Screenshot2022-04-17at152423.jpg\"\u003e\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/div\u003e","brand":"London Vet Show 2025","offers":[{"title":"Default Title","offer_id":56663800119669,"sku":null,"price":19.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0102\/9989\/9959\/files\/VSA_7_3d1a93d4-3a91-4bcc-a494-94780e974cf5.png?v=1769688015","url":"https:\/\/academy.vetshow.com\/products\/what-have-we-learned-from-treating-melanomas-lvs25","provider":"Vet Show Academy","version":"1.0","type":"link"}